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has been cited by the following article:

• TITLE: Rotavirus, Norovirus and Astrovirus in Children Aged 0 - 5 Years: Evolution of Prevalence over 10 Years (2013-2023) Following the Introduction of Rotavirus Vaccines in Burkina Faso

  AUTHORS: Dako Dakouo, Abdoul Karim Ouattara, Djénéba Ouermi, Mah Alima Esther Traore, Théodora Mahoukèdè Zohoncon, Mamoudou Sawadogo, Nadia Léticia Zigani, Naguesba Issoufou Tao, Lassina Traore, Teega-Wendé Clarisse Ouedraogo, Rogoménoma Alice Ouedraogo, Ali Kande, Zakaria Gamsonre, Prosper Bado, Denise P. Ilboudo, Albert Théophane Yonli, Florencia Wendkuuni Djigma, Jacques Simpore

  KEYWORDS: Rotavirus, Norovirus, Astrovirus, Gastroenteritis, Rotavirus Vaccines, Burkina Faso

  JOURNAL NAME: American Journal of Molecular Biology, Vol.14 No.4, September 29, 2024

  ABSTRACT: Rotaviruses, noroviruses, and astroviruses are responsible for gastroenteritis in children under 5 years old. The objective of our study was to estimate the evolution of prevalence of rotavirus, norovirus and astrovirus infections in children aged 0 to 5 years with gastroenteritis, after the introduction of rotavirus vaccines in Burkina Faso. This cross-sectional study was conducted between January and December 2023, collecting 100 stool samples from children with gastroenteritis at Saint Camille Hospital in Ouagadougou and the Charles De Gaulle University Paediatric Hospital. Noroviruses and astroviruses were detected using multiplex real-time PCR with a Sacace biotechnology detection kit. Data analysis was performed with Stata statistical software, version 16.0. The prevalence of norovirus infections was 14% and astrovirus infections were 9%. Rotavirus infections were found at prevalence of 15%. The age group most affected by norovirus and astrovirus infections was 0 - 12 months, with respective prevalence rates of 73.34% and 55.56%. The most frequently observed clinical signs in children infected with astrovirus were fever (77.78%), diarrhea (55.56%), and vomiting (44.44%). The introduction of rotavirus vaccines has reduced rotavirus-related infections. However, this has not significantly impacted the prevalence of norovirus and astrovirus infections in Burkina Faso.