Yu, J., et al. (2014) Structures of AzrA and of AzrC Complexed with Substrate or Inhibitor: Insight into Substrate Specificity and Catalytic Mechanism. Acta Crystallographica Section D: Biological Crystallography, 70, 553-564.
https://doi.org/10.1107/S1399004713030988

has been cited by the following article:

• TITLE: Application of a Pulsed Electric Field to Modify the Free Energy of the Active Site of an Azoreductase

  AUTHORS: Jesus Magyber de Jesus Miranda, Pedro Guillermo Reyes-Romero, Jorge Mulia-Rodríguez, Daniel Osorio-González

  KEYWORDS: Pulsed Electric Field, Molecular Dynamics, Docking, Azoreductase

  JOURNAL NAME: Journal of Applied Mathematics and Physics, Vol.12 No.1, January 31, 2024

  ABSTRACT: The Gibbs free energy is strongly related to the stability and catalytic function of an enzyme through the energetic changes that occur in the chemical reactions the enzyme catalyzes. In this in silico study, a pulsed electric field was applied to an azoreductase, and its effect on the Gibbs free energy of molecular docking with two dyes was measured. We propose that certain stimuli from a pulsed electric field favor the structural stability of the enzyme by promoting an arrangement in the active site, potentially leading to an enhancement of enzymatic activity overall.