TITLE:
Pleomorphic Nasopharyngeal Liposarcoma: An Aggressive Tumor
AUTHORS:
Mame Sanou Diouf, Sall Ahmadou Cheikhou, Ndiaye Ciré, Thiam Amadou, Abdoulaye Diop, Deguenonvo Richard Edouard Alain, Diom Evelyne Siga, Ndiaye Malick, Diallo Bay Karim, Diouf Raymond
KEYWORDS:
Liposarcoma, Nasopharynx, Pathology, Immunohistochemistry
JOURNAL NAME:
International Journal of Otolaryngology and Head & Neck Surgery,
Vol.13 No.1,
January
10,
2024
ABSTRACT: Nasopharyngeal liposarcoma is an extremely rare clinical entity. Less than ten cases have been reported in the literature. It mainly occurs in humans. The non-specificity of the clinical and radiological signs explains the difficulty of the diagnosis confirmed by anatomopathological and immunohistochemical examinations. Its pathogenesis remains obscure and often correlates with genetic abnormalities. Pleomorphic liposarcoma is its rarest subtype, remarkable for its aggressiveness and rapidity of growth. Complete surgical excision remains the treatment of choice. We report a case of liposarcoma whose diagnosis was made during histological examination coupled with immunohistochemistry.