TITLE:
Sinonasal Non-Intestinal-Type Adenocarcinoma: A Case Report
AUTHORS:
Mouhamad Ezadine, Moad El Mekkaoui, Razika Bencheikh, Anas Benbouzid, Abdelilah Oujilal, Leila Essakalli
KEYWORDS:
Endoscopic Surgery, High Grade Adenocarcinoma, Immunohitochemistry, Low-Grade Adenocarcinoma, Radiotherapy, Sinonasal Malignancies, Sinonasal Non-Intestinal-Type Adenocarcinoma
JOURNAL NAME:
Voice of the Publisher,
Vol.9 No.4,
December
26,
2023
ABSTRACT: Non-intestinal-type adenocarcinoma (non-ITAC) is defined as an adenocarcinoma that can arise anywhere in the sinonasal tract does not show features of salivary gland neoplasia, and does not have an intestinal phenotype. We report a case of a 79-year-old patient treated for colorectal cancer with lung metastasis by surgical excision and chemotherapy, who presented recurrent episodes of epistaxis evolving over more than 4 years. Her clinical examination showed a mass on the left nasal cavity. The computed tomography (CT) scan showed a locally aggressive left ethmoido-nasal mass. Magnetic resonance imaging (MRI) showed a process of the nasal fossae and the left posterior ethmoidal cells. The patient was treated surgically with a middle meatotomy with anterior ethmoidectomy of the left nasal cavity, the surgical specimen was sent for a histological examination which confirmed the diagnosis of sinonasal non-ITAC. In Conclusion, non-ITACs are a rare type of tumor and are treated by complete surgical excision. Extensive disease or higher histologic grade may require adjunctive radiotherapy. The prognosis is determined by histologic grading: low-grade tumors are relatively indolent, whereas high-grade tumors confer a greater risk of recurrence and death.