S. Y. Lee, K. H. Park, J. W. Choi, J. K. Kwon, D. R. Lee, M. S. Shin, J. S. Lee, C. E. You and M. Y. Park, “A Prospective, Randomized, Placebo-Controlled, Double Blind- ed and Split-Face Clinical Study on LED Phototherapy for Skin Rejuvenation: Clinical, Profilometric, Histologic, Ultrastructural and Biochemical Evaluations and Comparison of Three Different Treatment Settings,” Journal of Photochemistry and Photobiology, Vol. 88, No. 1, 2007, pp. 51-67. doi:10.1016/j.jphotobiol.2007.04.008

has been cited by the following article:

• TITLE: Evaluation of the Safety and Efficacy of a Novel Home-Use Device with Diode Arrays and Contact Heating for Facial Skin Rejuvenation

  AUTHORS: J. Shaoul, R. S. Mulholland

  KEYWORDS: LED, Home-Use, Photo-Aging, Anti-Aging

  JOURNAL NAME: Journal of Cosmetics, Dermatological Sciences and Applications, Vol.1 No.4, December 1, 2011

  ABSTRACT: Background: Phototherapy of photoaged skin has been attempted by lasers or intense pulsed light at the visible or near-infrared part of the spectrum. The use of red Light-Emitting Diodes (LED) delivering a low dose energy to the skin has been described for office and home use. Methods: In the present study, a portable home-use device is presented that combines fractional non-thermal red LED with mild contact heating. Forty subjects aged 30 - 55 presenting with facial lax skin, large pores, fine lines, wrinkles and brown pigmentation received 8 bi-weekly treatments for 4 weeks, using the Silk’n Reju/FaceFX device (Home Skinovations, Yokneam, Israel). Skin condition was evaluated before and 1, 2, and 3 months following the last treatment session. Grading of outcome was done according to an independent blinded evaluator and patient satisfaction. Results: Facial skin improvement of wrinkling and skin texture were apparent immediately and scored clinically after 3 months as excellent and considerable by >90% of patients. Pigmentation improvement was less apparent. Overall facial skin improvement was noted by 77% of patients. Conclusions: The combination of fractional red LED and mild contact heating, using an at home portable device, proved to be safe and effective method to improve the quality of photoaged skin.