TITLE:
Gut Microbiota and Metabolic Diseases
AUTHORS:
Qianqian Tang, Maogong Tang
KEYWORDS:
Gut Microbiota, Microbiota-Gut-Brain Axis, Metabolic Diseases, Interventions
JOURNAL NAME:
Journal of Biosciences and Medicines,
Vol.10 No.11,
November
18,
2022
ABSTRACT: In this review, the characteristics of gut microbiota changes in 11 metabolic diseases, as well as the research progress on their interventions, are summarized. The gut microbiota contributes to metabolic diseases through intestinal mucosal dysfunction, chronic metabolic inflammatory response, gut brain axis imbalance, gene regulation, insulin resistance, and the action of its metabolites. The researches of cause effect relationship and mechanism are relatively few, need further study, expecting a breakthrough in the future to be a new path in the treatment of some metabolic diseases.