TITLE:
Promising Actions of Certain Medicinal Plants of Bangladesh against Diabetes and Oxidative Stress: A Review
AUTHORS:
Arghya Prosun Sarkar, Sozoni Khatun, Tonima Enam, Mst. Israt Jahan, Arjyabrata Sarker, Nilay Saha, Md. Ariful Islam, Shantanu Saha Sani
KEYWORDS:
Diabetes, Anti-Oxidant, Anti-Diabetic, Oxidative Stress, Medicinal Plants
JOURNAL NAME:
Pharmacology & Pharmacy,
Vol.13 No.10,
October
28,
2022
ABSTRACT: Diabetes
is a metabolic illness defined by hyperglycemia that affects 10% of the world’s
population. Diabetic complications such as blindness, kidney failure, and heart
failure can develop if left untreated and are made worse by oxidative stress.
Oxidative stress contributes to the rise of diabetic complications,
particularly type-2 diabetes. In the blood vessels of diabetic individuals, it
causes endothelial dysfunction. Diabetes is one of the leading causes of death
worldwide. Nowadays, it is alarming that the number of diabetic patients is
increasing dramatically. There are plenty of anti-diabetic drugs available on
the market, but they possess several adverse effects and do not completely cure
diabetes. It has now become a financial burden on patients, their families, and
society as well. Medicinal plants have gained popularity in developed and
developing countries over the last two decades because of their vast natural
sources and lack of harmful effects compared to modern allopathic medications.
According to the World Health Organization, traditional medicines, which are
mostly manufactured from plants, are still used by 80% of the population in
developing countries for the management and curing of diseases. This review
includes 81 Bangladeshi medicinal plants from 51 different families that can be
used to treat diabetes and oxidative stress. Among them, Psidium guajava (L.), Aloe vera, Catharanthus
roseus, Allium sativum, Annona squamosa, Cinnamon
zeylaniucm, Amaranthus esculentus, Eugenia jambolana, Azadirachta
indica, Moringa oleifera, Spondias
pinnata, Coccinia grandis (L.), Momordica charantia L.,
Heretiera fomes, Trigonella foenum-graecum were most potent. The fundamental purpose of our study is to
find out and highlight certain medicinal plants in Bangladesh that have
anti-diabetic and antioxidant capabilities so that the researchers can develop
newer anti-diabetic medications with minimal side effects to treat metabolic
dysfunction, diabetic complications, and oxidative stress more effectively.