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Zemel, B.S., Leonard, M.B., Kelly, A., Lappe, J.M., Gilsanz, V., Oberfield, S., Mahboubi, S., Shepherd, J.A., Hangartner, T.N., Frederick, M.M., Winer, K.K., Kalkwarf, H.J. (2010) Height Adjustment in Assessing Dual Energy X-Ray Absorptiometry Measurements of Bone Mass and Density in Children. The Journal of Clinical Endocrinology & Metabolism, 95, 1265-1273.
https://doi.org/10.1210/jc.2009-2057
has been cited by the following article:
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TITLE:
Bone Health in Pediatric Fracture Patients: A DEXA Study
AUTHORS:
Barbara Minkowitz, Jennifer Ristic, Leah Nadel, Meghan McDermott, Violet Wallerstein, Eileen Poletick
KEYWORDS:
Bone Health, Pediatric, Fracture, Vitamin D, DEXA, Osteoporosis, Osteopenia, Vitamin D Deficiency
JOURNAL NAME:
Open Journal of Orthopedics,
Vol.12 No.2,
February
23,
2022
ABSTRACT: Vitamin D deficiency is widespread in children and is associated with
increased fracture severity. Previous studies have shown mixed results on the
impact of vitamin D supplementation on bone
health parameters measured on dual-energy x-ray absorptiometry (DEXA) scan.
This is the first longitudinal DEXA study in a pediatric fracture population.
Pediatric fracture patients with vitamin D levels below 20
ng/mL were counseled to take vitamin D and calcium per a serum-based protocol.
Patients underwent baseline DEXA within the initial 12 weeks post fracture and
had follow-up scans at 6 and 12 months. 48 patients were enrolled, 32 patients
completed two DEXA scans, and 19 completed three DEXA scans. There was a
significant increase in lumbar spine BMC,
TBLH BMD, and TBLH BMC between DEXA 1 and 2 (p 0.001). A
positive trend in DEXA parameters is suggested between DEXA 1 and DEXA 3.
Height adjusted z-scores (HAZ) were calculated which showed no statistical significance,
p-values > 0.05. In this group, there are no significant changes in TBLH, BMC or BMD
z-scores one year after fracturing despite
vitamin D and calcium supplementation. This suggests that children returning to
collision sports may be at continued risk for refracture and future studies are
needed.