Theologou, S., Ischaki, E., Zakynthinos, S.G., Charitos, C., Michopanou, N., Patsatzis, S., et al. (2021) High Flow Oxygen Therapy at Two Initial Flow Settings versus Conventional Oxygen Therapy in Cardiac Surgery Patients with Postextubation Hypoxemia: A Single-Center, Unblinded, Randomized, Controlled Trial. Journal of Clinical Medicine, 10, 2079.
https://doi.org/10.3390/jcm10102079

has been cited by the following article:

• TITLE: Cardiac Postoperative Use of High-Flow Nasal Cannula: A Retrospective Single-Center Study

  AUTHORS: Emmanuel De Tandt, Marc Nauwynck

  KEYWORDS: Postoperative Respiratory Failure, Cardiac Surgery, HFNC, Noninvasive Ventilation, Reintubation

  JOURNAL NAME: Open Journal of Thoracic Surgery, Vol.12 No.1, February 15, 2022

  ABSTRACT: We aimed to investigate the risk factors and reason for initiation of high-flow nasal cannula (HFNC), its benefit on re-intubation rate, mortality, and length of stay (LOS) in the postoperative cardiac surgery patient in the ICU. Methods: In a retrospective and descriptive study, 200 patients, who underwent cardiac surgery, were randomly included, and screened for initiation of postoperative respiratory support. Demographic patient data and pre-operative patient measurements were sampled. Data concerning the P/F ratio at arrival- and post-extubation, LOS at ICU and overall mortality were sampled. A comparison of those variables was performed between patients with and without need of respiratory support. Results: HFNC was initiated in approximately 22.45% in 2018, and 25% in 2020, of the patients. Comparing both years didn’t reveal a significant rise, but we saw a quicker use of HFNC in 2020. The all-case re-intubation rate and mortality was approximately 3%. The body mass index (BMI) was the only correlation with a higher chance of initiation of HFNC. Other data like age, pre-operative renal- or left ventricle function didn’t show a correlation. Conclusion: In case of respiratory insufficiency in the postoperative cardiac surgery setting, HFNC is a worthy first line treatment option which is initiated if conventional oxygen therapy doesn’t suffice. The mortality was low, and the mean LOS was 4.38 days. If respiratory support was started with HFNC mean LOS rose to 8.35 days. The BMI seems to have a correlation with the development of respiratory failure, which confirms the latest recommendation to start preventive HFNC in the post-extubation cardiac surgery setting and which could be implemented in the daily practice.