Cox, J.L., Sexton, P.S., Green, T.J. and Darmani, N.A. (1999) Inhibition of B16 Melanoma Metastasis by Overexpression of the Cysteine Proteinase Inhibitor Cystatin C. Melanoma Research, 9, 369-74.
https://doi.org/10.1097/00008390-199908000-00005

has been cited by the following article:

• TITLE: Cystatin C Peptide Effects on B16F10 Melanoma Cells

  AUTHORS: Mathieu Hill, James L. Cox

  KEYWORDS: Cystatin, Peptide, Melanoma, Metastasis

  JOURNAL NAME: CellBio, Vol.10 No.1, March 17, 2021

  ABSTRACT: Background: Metastasis is a major problem for effective therapy of cancer. Small cysteine protease inhibitors, cystatins have been shown to be anti-metastatic for a number of different cancers. We have identified a small peptide of cystatin which exhibits anti-cancer properties for B16 melanoma cells in vitro. Methods: B16 melanoma cells were measured for growth, proliferation, migration, and apoptosis in the presence and absence of cystatin peptide. Results: The cystatin peptide reduced melanoma cell growth, proliferation, migration, and increased apoptosis in melanoma cells in culture. Conclusion: Cystatin peptide exhibits anti-cancer effects on highly metastatic B16 melanoma cells in culture.