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has been cited by the following article:

• TITLE: An index for evaluating distance of a healthy heart from Sino-Atrial blocking arrhythmia

  AUTHORS: Hossein Gholizade-Narm, Morteza Khademi, Asad Azemi, Masoud Karimi-Ghartemani

  KEYWORDS: Healthy Heart; Blocking Arrhythmia; Perturbation method; Synchronization Boundary; Optimization; Bifurcation

  JOURNAL NAME: Journal of Biomedical Science and Engineering, Vol.3 No.3, April 9, 2010

  ABSTRACT: In this paper, an index for evaluating Distance of a healthy heart from Sino-Atrial Blocking Arrhythmia (SABA) is presented. After definition of the main pacemakers' model of heart, Sino-Atrial (SA) and Atrio-Ventricular nodes (AV), the boundary of synchronization, which demonstrates the boundary of blocking arrhythmia, is obtained using perturbation method. In order to estimate of healthy heart characteristics, a parameter estimator is introduced. The distance from SABA is calculated using Lagrange method and Kohn-Tucker conditions. In addition, the maximum admissible decrease in the coupling intensity and the maximum admissible increase in the discrepancy between the natural frequencies of two pacemakers are determined in order to maintain the synchronization between the two pacemakers.