TITLE:
Studies and Mechanism of Olefination Reaction in Aryl-Enolates with Paraformaldehyde
AUTHORS:
Jonathan Román Valdéz-Camacho, José Domingo Rivera-Ramírez, Jaime Escalante
KEYWORDS:
Olefination, Paraformaldehyde, α-Aryl-α, β-Unsaturated Ester, α-Methylenation
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.9 No.1,
January
17,
2019
ABSTRACT: A simple, efficient and
low-cost methodology for the synthesis of α-aryl-α,β-unsaturated esters using paraformaldehyde as a
source of carbon was developed. Factors that control reaction yields such as
temperature, concentration and reaction time were evaluated. A mechanism is
proposed based on experimental structures of the intermediates.