TITLE:
The Antibacterial and Antioxidant Effect of Salvadora persica on Antibiotic Resistant Strains
AUTHORS:
Z. Mammad, S. Hsaine, T. Djassinra, K. Ounine
KEYWORDS:
Salvadora persica, Pseudomonas aeruginosa, Acinetobacter baumannii and Enterobacter cloacae, Extract, Soxhlet, DPPH, Antioxidant, Ascorbic Acid
JOURNAL NAME:
American Journal of Plant Sciences,
Vol.9 No.7,
June
25,
2018
ABSTRACT: Many efforts have been devoted to studying the
inhibitory effect of Salvadora persica (Miswak) on oral microorganisms. However,
information regarding its antibacterial activity against other human pathogens is
rare. Particularly, against Pseudomonas aeruginosa, Acinetobacter
baumannii and Enterobacter cloacae. The purpose of this piece of work was to evaluate
the antioxidant power and in vitro antibacterial activities of Salvadora persica extract against the three bacterial clinical isolates mentioned above.
Therefore, the action of Salvadora persica extract on the three germs, studied via the aromatograms
method, has given an inhibition zone 20, 18 and 14 respectively on Pseudomonas aeruginosa, Acinetobacter baumannii and Enterobacter cloacae. The methanol extract of Salvadora persica using Soxhlet has given an output of 19%. The antioxidant evaluation,
which was performed using the DPPH (1,1-diphenyl-2-picryl-hydrazyl), free
radical scavenging method, indicated that the methanol extract showed good
antioxidant efficiency (IC50 = 15.47 mg/ml) compared to ascorbic acid with
(IC50 = 0.097 mg/ml).