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http://www.ncbi.nlm.nih.gov/pubmed/22546131

has been cited by the following article:

• TITLE: Evaluation of the Efficacy of Liposomal Bupivacaine Infiltrated into the Posterior Capsule for Postoperative Analgesia after Total Knee Arthroplasty—A Randomized Double Blind Clinical Trial

  AUTHORS: Mohit Garg, Piyush Gupta, Kevin Kang, Avichai Dukshtein, Dennis Feierman

  KEYWORDS: Liposomal Bupivacaine, Exparel, Knee Arthroplasty

  JOURNAL NAME: Open Journal of Anesthesiology, Vol.7 No.11, November 29, 2017

  ABSTRACT: Achieving adequate control of postsurgical pain remains a challenge in patients undergoing Total Knee Arthroplasty (TKA). The objective of this study was to assess if liposomal bupivacaine injected into the posterior capsule, in combination with a femoral nerve block and multimodal pain control regimen, would result in better pain control. The two groups were similar with regards to demographics and method of intraoperative anesthesia. Infiltration into the posterior capsule with liposomal bupivacaine had significantly lower resting pain scores compared to the saline group. Patients in the liposomal bupivacaine group also used slightly less breakthrough narcotic (5.75 to 4.31 mg of morphine equivalence). We recommend the use of infiltration of liposomal bupivacaine into the posterior capsule as an adjunct in multimodal analgesia in TKA patients to reduce pain and resultant narcotic use.