TITLE:
Study of Diffusion through the Skin of Coated L-Ascorbic Acid by Fluid Bed Technology
AUTHORS:
Ferrándiz Marcela, Capablanca Lucía
KEYWORDS:
pH Dependent Polymer, L-Acid Ascorbic, Diffusion, Fluid Bed
JOURNAL NAME:
Journal of Encapsulation and Adsorption Sciences,
Vol.7 No.2,
June
12,
2017
ABSTRACT: Coating protects substances such as L-ascorbic acid from natural processes like oxidation. In this study, L-ascorbic acid was coated by fluid bed technology. A pH-dependent polymer was used as a coating material in order to release L-ascorbic acid (dissolution above pH 5.5) under conditions closest to the skin’s natural condition. Different techniques were used to determine the coating (SEM and size distribution) and to evaluate the percentage of coated L-ascorbic acid and its diffusion through the skin.