TITLE:
Renal Manifestations among Adult Sickle Cell Disease Patients: A Single Center Study in Khartoum, Sudan
AUTHORS:
Amin S. Banaga, Hala I. Elhardlu, Khalifa Elmusharaf
KEYWORDS:
Sickle Cell Disease, Renal Manifestations, Sudan
JOURNAL NAME:
Open Journal of Nephrology,
Vol.6 No.4,
December
19,
2016
ABSTRACT: Sickle Cell Disease (SCD) in
adults is one of the causes of renal abnormalities and Chronic Kidney Disease (CKD). In this retrospective study, we explore the renal
manifestations among adult SCD patients. The subjects of the study are all
adult patients diagnosed with sickle cell anaemia and admitted as to the
Academy Charity Teaching Hospital,
Khartoum/Sudan during the period (01/01/2015-31/12/2015). All adult SCD
patients’ medical files have been reviewed focusing on personal and clinical
data in addition to presence or absence of renal manifestations, a total of 51
adult patients with SCD have been admitted to
Academy Charity Teaching Hospital, Khartoum/ Sudan. 11 patients have
renal manifestations (21.5%). The mean age ± SD of SCD patients with renal
manifestations was 20.2 ± 1.9 years, 63.6% were males, the mean Hb level was
6.9 ± 0.99 gm/dl, proteinuria was present among 81.8% of patients, followed by haematuria
(36.4%) and End Stage Renal Failure
(ESRF) (18.2%). Further prospective studies are needed to explore the
renal abnormalities among adult SCD patients.