TITLE:
Clinical Behavior of Dengue and Chikungunya Infections in the Instituto Mexicano del Seguro Social
AUTHORS:
Joel Navarrete-Espinosa, Joaquín Gonzalez-Ibarra, Clara E. Santa Cruz-Tinoco, Cesar R. Gonzalez-Bonilla, Miguel Pacheco-Hernández, José E. Muñoz-Medina
KEYWORDS:
Chikungunya, Behavior, Clinical
JOURNAL NAME:
Open Journal of Medical Microbiology,
Vol.6 No.1,
March
21,
2016
ABSTRACT: Arbovirus infections have increased worldwide in the last years and specific differential diagnosis may be difficult owing to their similar clinical presentations. Here we describe and compare the clinical manifestations of dengue and chikungunya fever. Material and Methods: In order to portray the clinical behavior of both diseases, a cross-sectional study was performed including patients insured by the Mexican Institute for Social Security (IMSS), their demographic data, and clinical signs and symptoms. Laboratory parameters were analyzed. Results: One thousand four hundred and ninety-five dengue and 1810 chikungunya cases were studied. All patients presented fever, whereas headache, myalgias, mild arthralgias, and ocular pain were more frequent in dengue cases. Severe incapacitating polyarthralgias, arthritis, and conjunctivitis were present only in chikungunya cases. Also, edema and exanthema were more frequent in patients with chikungunya. Liquid leak to tissues and hemorrhage were more frequent among dengue cases. Platelet counts were lower in hemorrhagic dengue (P