TITLE:
New Method for Preparation of 1-Amidoalkyl-2-Naphthols via Multicomponent Condensation Reaction Utilizing Tetrachlorosilane under Solvent Free Conditions
AUTHORS:
Samy B. Said, Mohammad M. A. Mashaly, Ahmed M. Sheta, Saad S. Elmorsy
KEYWORDS:
1-Amidoalkyl-2-Naphthol, Tetrachlorosilane (TCS), Multicomponent Reaction
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.5 No.3,
September
14,
2015
ABSTRACT: An efficient and direct procedure for the synthesis of amidoalkylnaphthol derivatives employing a multi-component and one-pot condensation reaction of 2-naphthol, aromatic aldehyde and ace-tonitrile in the presence of tetrachlorosilane (TCS). A binary reagent from (TCS)/ZnCl2 was used upon applying benzonitrile.