TITLE:
Disseminated Presentation of Primary Lymphoblastic Lymphoma of the Bone in a Pediatric Patient
AUTHORS:
Lisa A. Cao, Alya Sheikh, Xin Qing, Samuel French, Joseph L. Lasky, Eduard H. Panosyan
KEYWORDS:
Primary Lymphoma of Bone, Pediatric Musculoskeletal Tumor
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.6 No.6,
June
30,
2015
ABSTRACT: Primary non-Hodgkin’s lymphoma of the bone (PLB) is extremely rare in the
pediatric population with less than 100 cases reported in the English
literature. Most commonly, patients present with atraumatic bone pain and
grossly normal radiographic findings. PLB is in the histopathological class of
“small round cell tumors of bone”, as with most common bone tumors. The
diagnosis is confirmed by immunohistochemical or flow cytometry based detection
of tumor-specific proteins. We present a case of stage IV PLB of
B-lymphoblastic type with an excellent response to chemotherapy to increase
awareness among general pediatricians and pathologists about the importance of
making the correct diagnosis, given the excellent prognosis for this disease.