TITLE:
Solvent-Free Synthesis of Carboxylic Acids and Amide Analogs of CAPE (Caffeic Acid Phenethyl Ester) under Infrared Irradiation Conditions
AUTHORS:
Pablo A. Martínez-Soriano, José R. Macías-Pérez, Ana María Velázquez, Brígida del Carmen Camacho-Enriquez, Gustavo Pretelín-Castillo, Mónica B. Ruiz-Sánchez, Víctor H. Abrego-Reyes, Saúl Villa-Treviño, Enrique Angeles
KEYWORDS:
Amides, Carboxylic Acids, Amines, Infrared Light, Solventless, CAPE, CAPA, Cinnamic Acid Analogs
JOURNAL NAME:
Green and Sustainable Chemistry,
Vol.5 No.2,
May
4,
2015
ABSTRACT: A convenient and easy method is described for the formation of carboxamides from carboxylic acids and primary amines in solventless conditions using infrared (IR) light. Thus, under IR light, cinnamic acid derivatives and amines can produce yields ranging from 50% to 85% of the resulting amide.