TITLE:
Nailfold Capillaroscopy Findings in Diabetic Patients (A Pilot Cross-Sectional Study)
AUTHORS:
Alireza Rajaei, Pooneh Dehghan, Zahra Farahani
KEYWORDS:
Diabetes, Nail Fold Capillaroscopy, Normal Pattern, Scleroderma PatternDiabetes, Nail Fold Capillaroscopy, Normal Pattern, Scleroderma Pattern
JOURNAL NAME:
Open Journal of Pathology,
Vol.5 No.2,
April
24,
2015
ABSTRACT: Background: Microcirculation is affected in
diabetes mellitus and Microvascular abnormalities cause persistent diabetic
complications. The aim of this study was nailfold capillaroscopic assessment
to describe the pathological changes (morphological and structural) in
capillary of a large series of patients with type 1 and 2 diabetes. Methods: A
cross-sectional study was carried out in a Nailfold Capillaroscopy Center
(Tehran-Iran) between 2011 and 2014. The study included 235 types 1, 2 diabetic
patients. All patients underwent 10 nailfolds capillaroscopy examinations.
Microvascular architecture, disturbances capillary distribution, capillary
morphology, capillary density, efferent/afferent limb ratio, subpapillary
venular plexus, and morphological abnormalities were evaluated. Conclusions
were stated as normalor scleroderma pattern. Results of patients’
capillaroscopic images were recorded and analyzed quantitatively and qualitatively.
P value