TITLE:
Why Ben-Naim’s Deepest Pitfall Does Not Exist
AUTHORS:
Yi Fang
KEYWORDS:
Protein Folding, Gibbs Free Energy, Quantum Mechanics, Statistical Mechanics
JOURNAL NAME:
Open Journal of Biophysics,
Vol.5 No.2,
April
17,
2015
ABSTRACT: Ben-Naim
warns that there are pitfalls in pursuing Anfinsen’s thermodynamic hypothesis.
We show that the deepest one of his pitfalls is not a pitfall at all and the
believing pursuing the minimum of the Gibbs free energy will lead us to the
native structure. The “pitfall” came from the flawed inference of Gibbs energy
function and the muddiness on concepts such as thermodynamic system and the
second law of thermodynamics.