Taieb, A., Alomar, A., Bohm, M., Dell’Anna, M.L., De Pase, A., Elefttheriadou, V., Ezzedine, K., Gauthier, Y., Gawkrodger, D.J., Jouary, T., Leone, G., Moretti, S., Nieuweboer-Krobotova, L., Olsson, M.J., Parsad, D., Passeron, T., Tanew, A., van der Veen, W., van Geel, N., Whitton, M., Wolkerstorfer, A. and Picardo, M. (2013) Guidelines for the Management of Vitiligo: The European Dermatology Forum Consensus. British Journal of Dermatology, 168, 5-19. http://dx.doi.org/10.1111/j.1365-2133.2012.11197.x

has been cited by the following article:

• TITLE: Preliminary Colorimetric Assessment of Progressive Nonsegmental Vitiligo under Short-Term Intravenous Methylprednisolone Pulse Therapy

  AUTHORS: Yuiko Nagata, Atsushi Tanemura, Emi Ono, Aya Tanaka, Kenichi Kato, Mizuho Yamada, Ichiro Katayama

  KEYWORDS: Intravenous Methylprednisolone Pulse Therapy, Progressive Nonsegmental Vitiligo, Spectrophotometer

  JOURNAL NAME: Journal of Cosmetics, Dermatological Sciences and Applications, Vol.4 No.3, May 16, 2014

  ABSTRACT: Although the administration of systemic steroid for nonsegmental vitiligo in the progressive stage is a recommended treatment according to guidelines, the clinical efficacy of this regimen has not been fully established. In this study, we evaluated the clinical efficacy of half-dose steroid treatment and stratified the evidence regarding its usefulness in progressive vitiligo patients. Half-dose steroid pulse therapy (500 mg/day of methylprednisolone for three sequential days) was administered intravenously three times monthly in five vitiligo patients. The visual changes in vitiligo lesions were evaluated on photographs and quantified using a spectrophotometer. As results, all patients completed three cycles of treatment without severe adverse events. Three of the five patients achieved disease arrest with decrease in white contrast. Therefore, short-term and halfdose steroid therapy is well tolerated and effective for achieving disease arrest in progressive nonsegmental vitiligo. The whiteness assessed by a spectrophotometer is possibly associated with therapeutic response to steroid therapy.