TITLE:
Vibrational Studies of Different Human Body Disorders Using FTIR Spectroscopy
AUTHORS:
S. Kumar, Reena, S. Chaudhary, Sweety, Deep Chand Jain
KEYWORDS:
Fourier Transform Infrared (FTIR); ImmunoglobuinG (IgG); Epilepsy (E); Migraine (M); Paralysis (P); Alzheimer’s Diseases (AD); Duchenne Muscular Dystrophy (DMD)
JOURNAL NAME:
Open Journal of Applied Sciences,
Vol.4 No.3,
March
11,
2014
ABSTRACT: Some of the important features of the bands occur in the present study. The band called amide A is available in all the diseased and healthy controls and the frequency of the band ranges from 3380 cm﹣1 to 3480.74 cm﹣1. The band due to C-H band and called hydrocarbon band was found only in paralytic and Alzheimer diseased along with normal healthy controls. Carbide band (C=C) is found only in Duchenne muscular dystrophy, paralytic and Alzheimer’s disease patients. Amide I was intact in all disorders with normal persons. Peroxide band (O-O) was found in all the cases of study. Amide IV band was found in paralytic, muscular dystrophy, Alzheimer’s diseases and normal controls. The amide V band was found in Alzheimer’s diseases only. The appearance or disappearance of the bands is a good sign to understand the mechanisms at the molecular level. FTIR spectroscopy may help in the diagnosis of the disease at the early stage of the onset. This spectroscopy can be used nicely for the study of hair, vaginal fluid, nails, urine, mucus, semen, synovial fluid, blood, hemoproteins, skin, and tears for human beings. We can also use it to understand the effect of adulteration on food and paint technology. FTIR is an indicator to explore the changes occurring at molecular level.