Article citationsMore>>
D. J. Vugts, M. M. Koningstein, R. F. Schmtiz, F. J. J. kanter, M. B. Groen and R. V. A. Orru, “Multicomponent Synthesis of Dihydropyrimidines and Thiazines,” Chemistry—A European Journal, Vol. 12, No. 27, 2006, pp. 7178-7189. http://dx.doi.org/10.1002/chem.200600168
has been cited by the following article:
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TITLE:
Phase Transfer Catalysis Improved Synthesis of 3,4-Dihydropyrimidinones
AUTHORS:
Hela Slimi, Khemaïs Saïd, Younes Moussaoui, Ridha Ben Salem
KEYWORDS:
Multicomponent Reaction; Biginelli Reaction; 3, 4-Dihydropyrimidinones; Phase-Transfer Catalysis; Quaternary Ammonium Salts
JOURNAL NAME:
International Journal of Organic Chemistry,
Vol.3 No.3A,
November
28,
2013
ABSTRACT:
Various 3,4-dihydropyrimidinones can be prepared via Biginelli reaction in aqueous media by using quaternary ammonium salts of different alkyl groups (C4 and C8) and anions (Cl-and Br-) as catalysts. The use of quaternary ammonium salts along with longer alkyl chains increases the yield of the Biginelli reaction; however, bromide ammonium salts are less active than the chloride ones.