TITLE:
Transposable elements in Escherichia coli antimicrobial resistance
AUTHORS:
Archana Iyer, Elie Barbour, Esam Azhar, Alaaeddin Ali El Salabi, Hani Mutlak A. Hassan, Ishtiaq Qadri, Adeel Chaudhary, Adel Abuzenadah, Taha Kumosani, Ghazi Damanhouri, Maha Alawi, Tarek Na’was, Afif M. Abdel Nour, Steve Harakeh
KEYWORDS:
Transposable Elements; E. coli; Antimicrobial Resistance; Integrons
JOURNAL NAME:
Advances in Bioscience and Biotechnology,
Vol.4 No.3A,
March
29,
2013
ABSTRACT:
Transposable
elements are capable of switching their positions
on the genome thereby causing gene arrangements and contributing to
genome evolution. The aim of this review is
to specifically discuss the role of transposable elements in transferring
antimicrobial resistance genes in E. coli, thus contributing to increase
in virulence and conferring the possibility of multidrug resistance. Different
types of transposable elements such as transposons and integrons and their
profound influence on E. coli antimicrobial resistance are the focus of
this review.