Taira, S., Sugiura, Y., Moritake, S., Shimma, S., Ichiyanagi, Y. and Setou, M. (2008) Nanoparticle-assisted laser desorption/ionization based mass imaging with cellular resolution. Analytical Chemistry, 80, 4761-4766. doi:10.1021/ac800081z

has been cited by the following article:

• TITLE: Visualization of decreased docosahexaenoic acid in the hippocampus of rats fed an n – 3 fatty acid-deficient diet by imaging mass spectrometry

  AUTHORS: Shu Taira, Michio Hashimoto, Kazunori Saito, Osamu Shido

  KEYWORDS: Docosahexaenoic Acid; Imaging Mass Spectrometry; Fourier-Transform Ion Cyclotron Resonance Mass Spectrometry; Hippocampus

  JOURNAL NAME: Journal of Biophysical Chemistry, Vol.3 No.3, August 28, 2012

  ABSTRACT: The present study employed an imaging mass spectrometry (IMS) method to evaluate the effect of dietary n – 3 fatty acids on the fatty acid composition in rat brain. Rats were divided into two groups and fed either an n – 3 fatty acid-deficient or adequate diet. We determined the decreased n – 3 fatty acids in the hippocampus of rats fed an n – 3 fatty acid-deficient diet compared to the control. IMS visualization was achieved at a resolution of 100 m in rat brain, and showed decreased docosahexaenoic acid (DHA)-containing phosphatidyl choline (PC) or phosphatidyl ethanolamine (PE) in the hippocampus of rats fed an n – 3 fatty acid-deficient diet.