TITLE:
Fractionation and structural identification of antibiotic activity substances from Streptomyces herbaricolor HNS2-2
AUTHORS:
Lili Chen, Youzhi Li, Hongjian Zhu, Yuhua Liu, Bida Gao
KEYWORDS:
Streptomyces Herbaricolor HNS2-2; Quercetin Dehydrate; p-Hydroxyphenyl; 4-Hydroxyflavanone; 3-Hydroxyflavone; Bioactivity
JOURNAL NAME:
Agricultural Sciences,
Vol.3 No.4,
June
22,
2012
ABSTRACT: Four groups of antibiotic activity compounds were separated and purified from the ethyl acetate fraction of a broth culture of Streptomyces herbaricolor HNS2-2.Trace analyses were performed and anti-microbial activities were determined. The antibiotic activity compounds were identified as quercetin dehydrate ①, p-hydroxyphenyl ②, 4’-hydroxyflavanone ③, and 3-hydroxyflavone ④ based on spectroscopic data. Compounds 1-4 showed significant antimicrobial activities against Staphylococcus aureus and the tobacco mosaic virus in vitro, suggesting their potential agricultural and medical applications.