TITLE:
A Comparative Study of Myocardial Damage Caused by Novel Coronavirus Infection and Influenza A Virus Infection in Children during the COVID-19 Epidemic Period
AUTHORS:
Chong Liang, Guosheng Su, Chunhong Qiu, Lihua Qin, Yongkang Li, Jide Huang, Fangyue Pan, Fengming Meng, Huarong Pan, Chunjiao Nong
KEYWORDS:
COVID-19, COVID-19 Infection, Influenza A, Myocardial Damage
JOURNAL NAME:
Advances in Infectious Diseases,
Vol.14 No.2,
May
13,
2024
ABSTRACT: Objective: To explore the comparative study of myocardial damage in children infected with COVID-19 and influenza A virus during the COVID-19 pandemic. Method: Retrospective analysis of myocardial injury caused by COVID-19 infection and influenza A virus infection in children during the COVID-19 from October 2022 to May 2023, including 106 cases of COVID-19 infection, that is, the COVID-19 group; And 164 cases of influenza A virus infection, namely, H1N1 group; Two groups were tested for various indicators of myocardial enzyme spectrum, and the situation of myocardial injury was compared between the two groups. Result: In the enrolled cases, there was no statistically significant difference in the prevalence rate of men and women in the COVID-19 group (P > 0.05); There was no statistically significant difference in the average age between men and women (P > 0.05); The comparison of the incidence rates between males and females in the H1N1 group showed a statistically significant difference (P 0.05); There was no statistically significant difference in the average age between the two groups of girls (P > 0.05). A comparison between two groups of various indicators of myocardial enzyme spectra showed that the results of AST, α-HBDH and LDH were statistically significant (P 0.05). Conclusion: Both COVID-19 infection and influenza A virus infection in children have different degrees of myocardial damage, but COVID-19 infection causes more myocardial damage than influenza A virus infection, and influenza A virus is more prone to myocardial infarction, which deserves our attention.