TITLE:
Heart Failure-Like Reaction Is Likely Involved in the Feeding Behaviour of Blood-Sucking Leeches
AUTHORS:
Li Yang, Jiao Shu, Xiao Wang, Wei Yu, Debin Wang, Zichao Liu, Bin Wang
KEYWORDS:
Blood-Sucking Leeches, Transcriptomic Analysis, Heart Failure, Feeding Behaviour
JOURNAL NAME:
Advances in Bioscience and Biotechnology,
Vol.15 No.1,
January
29,
2024
ABSTRACT: Medicinal leeches have been utilized in therapy for
thousands of years. However, the adaptation physiology between leeches and
hosts is not fully understand. To disclose
the molecular mechanisms of adaptation between leech and host, the
body transcriptomes of hunger and fed blood-sucking Poecilobdella javanica, Haemadipsa cavatuses, and Hirudo nipponia leeches were obtained by RNA sequencing, after comparison, a stratified
unigenes group was obtained, which closely correlated to body distension. In
the group, Rfamide receptor decreased significantly (P P. javanica and in strongest reaction of diastole in fed H. nipponia. Overall,
heart failure is likely a physiological function involved in
feeding behaviour.