TITLE:
Enteropathica Acrodermatitis Complicated by Necrotising Fasciitis in an Infant Admitted to the Paediatric Emergency Department of the Gabriel Touré University Hospital
AUTHORS:
Aichata Keita, Bory Traoré, Adama Dembélé, Rokiatou Diarra, Mariam Diarra, Elmouloud M. Cissé, Mariam Kané, Bakary Coulibaly, Hawa Konaré
KEYWORDS:
Enteropathica Acrodermatitis, Necrotizing Fasciitis, Infant
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.13 No.6,
November
8,
2023
ABSTRACT: Acrodermatitis enteropathica is a rare autosomal recessive genetic
disorder characterised by periorificial dermatitis, alopecia and diarrhoea. It
is caused by a mutation in the gene that codes for a membrane protein that
binds zinc. We report a case in a 7-month-old girl, admitted with altered
general condition and scaly, pustular erythematous lesions, initially located
in the occipital and cervical regions, and secondarily inguinal and on the
knees. Management and outcome in this patient? Genetic
assay was not available to confirm this rare genetic disease. A delay
in establishing the diagnosis and a disastrous outcome did not save the patient
despite the administration of zinc.