TITLE:
Evaluation of Patients with Severe Aortic Stenosis after TAVI with Self-Expandable vs. Balloon-Expandable Devices
AUTHORS:
Mohammad Nourizadeh, Seifollah Abdi, Farideh Roshan Ali, Najmeh Assadinia, Mehdi Nourizadeh, Mohammad Emami, Elham Barati, Amir Taha Asarian
KEYWORDS:
TAVI, Balloon-Expandable Valves, Self-Expandable Valves, Mortality, Aortic Stenosis
JOURNAL NAME:
World Journal of Cardiovascular Diseases,
Vol.13 No.10,
October
10,
2023
ABSTRACT: Background: The introduction of transcatheter
aortic valve implantation (TAVI) for the treatment of severe aortic stenosis (SAS) has
expanded the therapeutic possibilities for successfully managing SAS in cases
with intermediate and high surgical risks. However, the complications and outcomes
of new devices have not been studied enough. Hence, the purpose of this study
is to evaluate the midterm results of the Core Valve and Evolute R self-expandable (SE) devices versus the Edwards SAPIEN
balloon-expandable (BE) devices. Methods and Material: This was a quasi-experimental study conducted in Tehran, Iran, from May
2012 to June 2017. SAS patients who were not ideal candidates for surgery were
randomly assigned to either SE or BE groups. For each patient, a questionnaire,
including four sections comprised of Basic
characteristics, echocardiographic, angiographic, and Computed
Tomography (CT) scan data was filled. TAVI was followed by echocardiography a
week later and after three months they were reevaluated by another
questionnaire. Results: The
total number of patients was 60. The mean ages of patients undergoing the
procedure with SE or BE devices were 81.2 ± 8 and 79.8 ± 7, respectively.
Mortality occurred in 20% of the patients (5 cases in the SE group and 7 cases
in the BE); mortality causes were 66.6 % cardiac and 33% non-cardiac. Moderate to severe Paravalvular leakage in both groups did
not differ significantly. The mortality rate was 5 (41.6%) in the SE group
versus 7 (58.3%) in the BE group (P > 0.05). Conclusion: In conclusion, the BE group did not experience
fewer paravalvular leaks in comparison with the SE. Morbidity and mortality
between the BE and the SE groups did not differ significantly.