TITLE:
Mechanisms and Associated Factors of Nocturia in Women Attending Two Urogynecology Clinics: A Cross-Sectional Study
AUTHORS:
Ingrid Antunes da Silva, José Rodrigo de Moraes, Renato Augusto Moreira de Sá, Carlos Augusto Faria
KEYWORDS:
Nocturia, Polyuria, Lower Urinary Tract Symptoms, Women’s Health
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.13 No.9,
September
20,
2023
ABSTRACT: Introduction: Nocturia has a
multifactorial etiology, and its diagnostic approach involves, in addition to
medical history and physical examination, the use of a bladder diary to define
the pathophysiological mechanisms present in each case. Methods: This study
investigated the prevalence of nocturia, its mechanisms,
and associated factors in women with lower urinary tract symptoms
attending two urogynecology clinics in the state of Rio de Janeiro, Brazil.
Anamnesis, physical examination, and a 24-hour bladder diary were conducted.
Two definitions of nocturia were considered: one or more nighttime voids and
two or more nighttime voids. Mann-Whitney and Chi-square tests were used, with
p-value ≤ 0.05 considered significant. Results: A
total of 133 participants were included. The majority were aged 60 years or
older (61.4%) and had three or more comorbidities (66.7%), with systemic
arterial hypertension being the most prevalent (59.1%). Of the total
participants, 54 (41.4%) completed the bladder diary. Among those with one or
more nighttime voids (70.7%), the prevalence of nocturnal polyuria was 69.1%,
reduced nocturnal bladder capacity was 17.3%, and global polyuria was 12.9%.
Among participants with two or more nighttime voids (56.4%), the prevalences
were respectively 68.2%, 19.1%, and 13.6%. Among the mechanisms, associations
were found only with global polyuria, namely: use of insulin, body mass index
and tobacco consumption. An association was also found between recurrent
urinary tract infection and global polyuria in participants with two or more
nighttime voids. Conclusions: The prevalence of nocturia was higher than that
reported in general population studies and specialized services for lower
urinary tract symptoms. Nocturnal polyuria was the most prevalent mechanism.
Associations were observed between the use of insulin, body mass index, tobacco
consumption, and recurrent urinary tract infection with global polyuria. No
associations were found between any clinical or demographic variables and
nocturnal polyuria or reduced nocturnal bladder capacity.