TITLE:
Transient Acantholytic Dermatosis: A Case Report and Literature Review
AUTHORS:
Shuxian Shang, Tenglong Li, Ying Yan, Ping Xia, Xiaoyong Zhou
KEYWORDS:
Acantholysis Cell, Transient Acantholytic Dermatosis
JOURNAL NAME:
Case Reports in Clinical Medicine,
Vol.12 No.9,
September
18,
2023
ABSTRACT: Transient acantholytic dermatosis (TAD, Grover disease) is a benign skin disease with a nonspecific rash that may present as a reddish-brown, dermatomal edematous papule or herpetiform rash with a partially central horny plug. This disease is usually self-limiting and can subside within weeks or months, but it may also have a chronic progression with a trend towards long-term recurrence. The patient is an 80-year-old male who visited the clinic due to recurring erythema and blisters all over his body that had been present for over 2 years. Based on the patient’s course, laboratory tests and histopathological findings were consistent with the diagnosis. The final diagnosis was transient acantholytic dermatosis. The patient has a long course of the disease, a wide range of skin lesions and he has the different subtypes of pathological manifestations. This case and corresponding literature review help us have a clear understanding of Grover’s disease, which has received reference value for the diagnosis and treatment of this disease in clinical work.