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has been cited by the following article:

• TITLE: Tympanometry Comparison of Diabetic Type I and Diabetic Type II Rats

  AUTHORS: Susan Amin, Ahmed Alaradi, Ahmed Alekri, Ali Alaysreen, Ammar Kheyami, Hasan Baksh, Khalid Nazzal, Abdullah Altamimi, Omar Alhamdan, Amer Kamal

  KEYWORDS: Diabetes, Tympanometry, Auditory Function, Compliance, Ear Canal

  JOURNAL NAME: Journal of Diabetes Mellitus, Vol.13 No.1, February 16, 2023

  ABSTRACT: Hearing impairment affects over two-thirds of adults with diabetes. We investigated whether rat models of type 1 and type 11 diabetes display impaired auditory function. Tympanometry measurements were conducted in Sprague-Dawley rats (control, n = 20), streptozotocin-induced type I diabetic Sprague-Dawley rats (n = 20) at 42 - 56 days old; Zucker rats (Hos: ZFDM-Lean (fa/+, n = 20) and Zucker Type 2 Diabetic rats (ZFDM (Hos: ZFDM-fa/fa); n = 20)), 90 days old. All rats were male. Control animals had normal type A tympanograms. Tweny one (75%) of the tympanic membranes in the diabetic type I group produced abnormal tympanograms: 46% were type B, 28% had no peak found, and 1% were type C. The ear canal measurements were lower in the left ear in type I mice (0.19 ± 0.07) and higher in the left ear for type II mice (0.23 ± 0.15 ml) compared to the controls of 0.39 ± 0.14 ml) and (0.2 ± 0.12 ml) respectively (P