TITLE:
Determinants of Prematurity at the Centre Hospitalier Universitaire Pédiatrique de Bangui (CHUPB)
AUTHORS:
C. J. Kiteze Nguinzanémou, B. O. Bogning Mejiozem, S. Ningatoloum Nazita, F. D. Fiobème, E. V. Ngatimo, J. E. Kosh-Komba Palet, I. M. Wando Kangalé, E. Kiteze Bandassa, S.-C.H. Diemer, J.-C. Gody
KEYWORDS:
Prematurity, CHUPB, Risk Factors
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.12 No.5,
November
23,
2022
ABSTRACT: Objective: The aim of this work was to identify the risk
factors for the occurrence of prematurity at CHUPB. Materials and Methods: a case-control study was performed between February and June 2021 at CHUPB. Our
study population consisted of premature infants who were matched to full-term
newborns on a 1:1 basis. The variables studied were maternal characteristics
(age, marital status, education level, and occupation) as well as pregnancy
(maternal history, prenatal care), delivery (maternal fever, rupture of membranes),
and newborns (gestational age, sex, and weight). The chi2 test with
a significance level of p 0.05 and the adjusted odds ratio were used. Results: A total of 609 newborns were hospitalized, 219 of whom were premature (36%), of
whom 100 premature infants meeting the inclusion criteria were enrolled.
Maternal age 18 years was noted in 20% of cases (adjusted OR = 2.94
[0.86 - 10.06]) versus 5% of controls. Low educational level
was noted in 47% (adjusted OR = 4.33 [1.88 - 9.96]) of cases versus 14% of controls. The
risk factors identified were previous preterm delivery (adjusted OR = 0.06 [0.00 - 0.80]), maternal fever before labor (adjusted OR = 0.43
[0.20 - 0.90]), and premature rupture of membrane (RPM),
(adjusted OR = 0.32 [0.16 - 0.64]). There was no association between marital
status and insufficient prenatal visits (ANC) in relation to the occurrence of
prematurity. Conclusion: The reduction of preterm births requires
improved monitoring of pregnancy, delivery and care of the newborn. But primary
prevention lies in improving the living conditions of the population.