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has been cited by the following article:

• TITLE: Chronic Recurrent Multifocal Osteomyelitis (CRMO): An Unusual Presentation of Limb Pain

  AUTHORS: Khadiza Tul Qubra, Mujammel Haque, Mohammad Imnul Islam, Shahana Rahman

  KEYWORDS: Bone Pain, CRMO, Multifocal Osteomyelitis

  JOURNAL NAME: Open Journal of Pediatrics, Vol.12 No.3, July 13, 2022

  ABSTRACT: Chronic recurrent multifocal osteomyelitis (CRMO), known as nonbacterial osteomyelitis, is an autoinflammatory disease with periodic exacerbations, also known as nonbacterial osteomyelitis. It is a rare, noninfectious inflammatory disorder characterized by multifocal bony lesions with pain. Conventional X-ray and CT imaging show multiple osteolytic and sclerotic lesions in the affected limbs. It is a great challenge for pediatricians to diagnose this disease for its rarity. Early diagnosis, regular follow-up and appropriate treatments are mandatory to reduce morbidity and prevent these disease complications. We report here two cases of CRMO who presented with pain, swelling and redness of multiple sites of lower limbs from the Department of Paediatrics, Bangabandhu Sheikh Mujib Medical University (BSMMU). Clinical features, laboratory findings, and characteristic radiological findings were strongly suggestive of CRMO.