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https://doi.org/10.1038/s41423-020-0488-6

has been cited by the following article:

• TITLE: Hypercalcemia and Granulomatous-Like Lesions in a Patient with Melanoma after Treatment with Immunotherapy: Case Report

  AUTHORS: Rebecca A. Takele, Alya Z. Aboulhosn, Prajwol Pant, Paul Laflam

  KEYWORDS: Hypercalcemia, Immune Checkpoint Inhibitors, Drug-Induced Sarcoido-sis-Like Reaction, Ipilimumab, Nivolumab

  JOURNAL NAME: Case Reports in Clinical Medicine, Vol.11 No.5, May 27, 2022

  ABSTRACT: Checkpoint inhibitors, a subset of immunotherapies, are effective treatment modalities for cancers such as melanoma. However, they are not without possible adverse effects. Drug-induced reactions may present with similar symptoms of sarcoidosis. We present the case of a 73-year-old female with a recent diagnosis of anorectal melanoma treated with checkpoint inhibitors who developed subsequent episodes of hypercalcemia. Her clinical symptoms along with her surgical cytology and radiologic results are characteristic of a drug-induced sarcoidosis-like reaction. With the increasing usage of immunotherapies in cancer treatment, it is important for clinicians to be aware of which patient population they are ideal for and possible adverse effects.