TITLE:
Assessment of Insulin Therapy in 281 Children and Adolescents with Type 1 Diabetes in Senegal
AUTHORS:
Djibril Boiro, Amadou Sow, Aliou Abdoulaye Ndongo, Idrissa Basse, Lamine Thiam, Ndiogou Seck, Cheha Fatoumia, Babacar Niang, Modou Guéye, Maïmouna Ndour Mbaye, Ousmane Ndiaye
KEYWORDS:
Diabetes, Children, Insulin Therapy, Senegal
JOURNAL NAME:
Open Journal of Pediatrics,
Vol.12 No.1,
March
31,
2022
ABSTRACT: Introduction: In Senegal, with the CDIC “Changing Diabetes In
children” project, insulin has been made free. The objective of this study was
to evaluate the accessibility and modalities of insulin therapy in the
management of type 1 diabetes. Methodology: This was a retrospective
study including patients followed for type 1 diabetes (T1DM) in
hospital between April 2018 and December
2020. Results: 281 patients were included. The mean age was 14.22 years.
The mean age at diagnosis was 11.28 years. Ketoacidosis was the main mode of
discovery of diabetes at 51.6%. Premix and rapid insulins were most commonly
used at 84.7% and 82.9% respectively, most often in combination. The most
commonly used treatment regimen was three injections/day in 82.5% of cases. The average daily insulin dose was 0.62 IU/Kg/dr. Of the patients, 219 (78%) were
self-monitoring of blood glucose. The average number of blood glucose checks
was 1.78 per day. 76 patients (27%) went days without an insulin
injection and up to 7 days in 51% of cases. The main reasons were forgetfulness, therapeutic errors and stock-outs.
Hypoglycaemia was observed in 14.2%. The average glycated haemoglobin was 10%. Conclusion: Despite the efforts made,
there are still challenges to improve access to insulin. The
reinforcement of therapeutic education on insulin therapy is essential for a better quality of life of diabetic children and
adolescents.