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https://doi.org/10.1021/ja0201909

has been cited by the following article:

• TITLE: Metal Complexes with 8-Hydroxyquinoline: Synthesis and In Vitro Antimicrobial Activity

  AUTHORS: Amira Cipurković, Emir Horozić, Snježana Marić, Lejla Mekić, Halid Junuzović

  KEYWORDS: 8-HQ, Metal Complex, Antimicrobial Activity, In Vitro Study

  JOURNAL NAME: Open Journal of Applied Sciences, Vol.11 No.1, January 11, 2021

  ABSTRACT: In this paper, three complexes with 8-hydroxyquinoline (8-HQ) were synthesized, their spectral analysis was performed and the antimicrobial effect was examined in vitro. The stoichiometric ratio of the complex was determined conductometrically and spectrophotometrically. FTIR and UV/VIS spectroscopy were used for structural characterization. Antimicrobial activity was examined by diffusion technique on selected gram-positive and gram-negative bacteria, and C. albicans. Square planar and octahedral geometry complexes were synthesized by mixing in a molar ratio of 1:2 (M:L). Based on the spectral data, it is concluded that both oxygen and nitrogen atoms from 8-HQ are involved in the formation of the complex. The antimicrobial activity of the complexes is high, with zones of inhibition in the range of 15 - 28 mm. 8-HQ was shown to have a significantly higher ability to inhibit the growth of the tested microorganisms.