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https://doi.org/10.1021/ac049198m

has been cited by the following article:

• TITLE: Thionization Method of Glycosyl Urea and Carbamide Sugars

  AUTHORS: Baktygul Ernazarova, Aida Bakirova, Asylkan Dzhumanazarova, Zhypargul Abdullaeva, Shamirbek Berkmamatov, Gulsara Zhusupbaeva

  KEYWORDS: Glycosyl Urea, Glycosyl Thiourea Synthesis, Lawesson’s Reagent, Anti-Inflammatory, Bactericidal, Fungicidal Properties

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.10 No.3, September 17, 2020

  ABSTRACT: This work is describing a thionization method for glycosyl urea and carbamide of sugars by using the Lawesson’s reagent. It is proposed the method based on the interaction of glycosyl urea and carbamide of sugars with the Lawessons reagent at a 1:1 ratio in the presence of a pyridine. As a result, sulfur-containing derivatives of sugar carbamides are obtained with the help of Lawesson’s reagent. Obtained experimental data are indicating the developed new method for thionization of sugar carbamides, which opens up broad possibilities for synthesis of various carbohydrate derivatives of thiourea. Significance of this work is that, thiourea derivatives are promising bactericidal, fungicidal and anti-inflammatory drugs. Therefore, the preparation of thiourea derivatives and the study of their properties remain topical tasks in the field of chemistry.