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https://doi.org/10.4236/nr.2016.73012

has been cited by the following article:

• TITLE: Synthesis and Bioactivity of 1-((2-Carbamoylguanidino) (furan-2-ylmethyl)urea

  AUTHORS: Chioma Donlawson, Daniel Okechukwu Nweneka, Kingsley John Orie, Reminus Okah

  KEYWORDS: Furfural, 1-((2-Carbamoylguanidino)(furan-2-ylmethyl)urea, Bioactivity

  JOURNAL NAME: American Journal of Analytical Chemistry, Vol.11 No.7, July 22, 2020

  ABSTRACT: 1-((2-Carbamoylguanidino)(furan-2-ylmethyl)urea was synthesised by coupling purified furfural with urea. The compound was characterized by GC-MS, FTIR, and 1H-NMR. The pathogens, Escherichia coli, Salmonella typhi, Staphylococcus aureus and Bacillus subtilis were isolated and screened with different concentrations of 1-((2-carbamoylguanidino)(furan-2-ylmethyl)urea. All the pathogens were susceptible to the synthesized compound except Bacillus subtilis. Due to this broad spectrum of activity, 1-((2-Carbamoylguanidino)(furan-2-ylmethyl))urea) can be use for various medicinal purposes and is therefore encouraged for the development of a novel drug in future.