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Heidari, A. (2017) Study of Synthesis, Pharmacokinetics, Pharmacodynamics, Dosing, Stability, Safety and Efficacy of Olympiadane Nanomolecules as Agent for Cancer Enzymotherapy, Immunotherapy, Chemotherapy, Radiotherapy, Hormone Therapy and Targeted Therapy under Synchrotorn Radiation. Journal of Developing Drugs, 6, e154. https://doi.org/10.4172/2329-6631.1000e154
has been cited by the following article:
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TITLE:
In Situ Characterization of Lopinavir by ATR-FTIR Biospectroscopy
AUTHORS:
Alireza Heidari
KEYWORDS:
ATR-FTIR Biospectroscopy, Simulation, Lopinavir, Breakdown, Coronavirus Disease-2019, COVID-19, Infection, Protective and Therapeutic Effect, Potent Drug
JOURNAL NAME:
Computational Chemistry,
Vol.8 No.3,
July
14,
2020
ABSTRACT:
Lopinavir is an antiretroviral of the protease inhibitor class (Figure 1 and Figure 2). It is used against HIV infections as a fixed-dose combination with another protease inhibitor, ritonavir (lopinavir/ritonavir). In the current research, the stimulated ATR-FTIR biospectroscopy of liquid sample of Lopinavir was investigated. The stimulated ATR-FTIR diffractions emitted through focusing the second harmonic laser beam Nd:YAG into the sample were recorded by Echelle spectrometer and ICCD detector. Increasing the energy of laser beam from 2.6 (mJ) to 16 (mJ) led to increase in stimulated ATR-FTIR signal but after breakdown threshold of liquid sample, further increasing energy led to the decrease in stimulating ATR-FTIR signals and for energies higher than 20 (mJ), they were disappeared.