Ramirez, P.T., Frumovitz, M., Pareja, R., Lopez, A., Vieira, M., Ribeiro, R., Buda, A., Yan, X., Shuzhong, Y., Chetty, N., Isla, D., Tamura, M., Zhu, T., Robledo, K.P., Gebski, V., Asher, R., Behan, V., Nicklin, J.L., Coleman, R.L. and Obermair, A. (2018) Minimally Invasive versus Abdominal Radical Hysterectomy for Cervical Cancer. The New England Journal of Medicine, 379, 1895-1904.
https://doi.org/10.1056/NEJMoa1806395

has been cited by the following article:

• TITLE: Total Laparoscopic Hysterectomy for Diagnosis and Treatment of Cervical Cystic Lesions: A Case Series

  AUTHORS: Tohru Morisada, Kohsei Tanaka, Tomoko Iijima, Azumi Nishizawa, Hiroshi Nishio, Yusuke Kobayashi, Masaru Nakamura, Shigenori Hayashi, Fumio Kataoka, Takashi Iwata, Daisuke Aoki

  KEYWORDS: Lobular Endocervical Glandular Hyperplasia, Minimum Deviation Adenocarcinoma, Total Laparoscopic Hysterectomy, Uterine Cervix

  JOURNAL NAME: Open Journal of Obstetrics and Gynecology, Vol.10 No.3, March 12, 2020

  ABSTRACT: Objective: Cervical cystic lesions are often observed in gynecological clinical practice. Many are caused by benign diseases such as lobular endocervical glandular hyperplasia (LEGH), and it is important to differentiate these lesions from those due to malignant diseases such as minimal deviation adenocarcinoma (MDA). In cases in which fertility preservation is not a concern, the final pathology is often confirmed by hysterectomy. To investigate the feasibility and safety of laparoscopic surgery for cervical cystic lesions, we retrospectively examined cases in which total laparoscopic hysterectomy (TLH) was performed for diagnosis and treatment. Methods: The subjects were 28 women who underwent TLH from April 2012 to March 2017 at Keio University Hospital. The pre- and post-operative courses of these patients were examined. Results: The average age was 49.4 (range 39 - 65) years and the mean body mass index was 21.7 (16.8 - 30.5) kg/m2. The average operation time was 159 (101 - 314) min and the average bleeding volume was 106.8 (0 - 600) g. There were no severe perioperative complications. The average hospital stay was 8.4 (7 - 14) days. In postoperative pathological diagnosis, 13 cases had benign diseases such as Nabot cysts, there were 14 cases of LEGH, and one patient was diagnosed with MDA. In the MDA case, additional bilateral salpingo-oophorectomy and pelvic lymph node dissection were performed at a later date. No metastasis was observed in these excised specimens. Conclusions: Our results suggest that TLH for cervical cystic lesions can be performed safely. However, it is important to consider the TLH indication before surgery based on the possibility of malignant disease.