TITLE:
Mucosal Schwann Cell Hamartoma—Colonic Lesion Susceptible to an Interesting Differential Diagnosis
AUTHORS:
J. Ortiz, L. Chinchilla, E. Muñoz, Md Ludeña
KEYWORDS:
Schwann Cell Hamartoma, Immunohistochemistry
JOURNAL NAME:
Open Journal of Pathology,
Vol.8 No.3,
July
18,
2018
ABSTRACT: We present a mucosal Schwann cell hamartoma that was observed in a 63-year-old woman with no personal or family history of interest who underwent a screening colonoscopy for early detection of colon cancer. During colonoscopy, a small polyp with a maximum diameter of 0.8 cm was detected at the rectosigmoid level. Histologically, a benign lesion of neuroid aspect was observed, consisting of multiple spindle cell fascicles that was positive for S-100 and negative for enolase, synaptophysin, CD34, CD117, actin, desmin, Dog1, EMA, and neurofilaments. These findings, supported by the family and personal history of the patient, allowed us to make a diagnosis, discarding other entities.