TITLE:
High Body Mass Has No Effect on Cellular and Innate Immunity in Siberian Hamsters (Phodopus sungorus)
AUTHORS:
Yufen Tian, Mengmeng Chen, Xiangdi Cui, Min Du, Qiuli Yu, Xiaokai Hu, Deli Xu
KEYWORDS:
Phytohaemagglutinin Response, Bacteria Killing Capacity, Body Fat, Glucose, Siberian Hamsters (Phodopus sungorus)
JOURNAL NAME:
Natural Science,
Vol.9 No.7,
July
25,
2017
ABSTRACT: Body mass is considered to be related with immune function in
animals. Our aim was to test the hypothesis that cellular and innate immunity
would be suppressed in high body mass of Siberian hamsters (Phodopus
sungorus). Six heavier (high body mass, HBM) and six lighter (low body
mass, LBM) hamsters were selected from 28 male hamsters. Body mass, body fat
mass, wet spleen mass and blood glucose levels were significantly higher in the
HBM group than in the LBM group. However, phytohaemagglutinin response, serum
bacteria killing capacity and white blood cells did not differ between the two
groups, suggesting cellular and innate immunity wasnot impaired in high
body mass of hamsters. There was no correlation between cellular, innate
immunity and body mass, body fat mass and glucose levels, suggesting cellular
and innate immunity wasnot suppressed by higher body mass, body fat mass and glucose
levels. In summary, cellular and innate immunity was not impaired in the HBM
hamsters compared with the LBM hamsters.