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https://doi.org/10.1016/0002-9378(95)90571-5

has been cited by the following article:

• TITLE: Postmenopausal Bleeding and Changing Bleeding Patterns after Parental Use of Corticosteroids: A Prospective Cohort Study

  AUTHORS: Henny Anna Rie Klomp, Johannes Maria Gulielmus Cobben, Paul Jan Quirien van der Linden

  KEYWORDS: Postmenopausal Bleeding, Corticosteroids, Bleeding Patterns

  JOURNAL NAME: Open Journal of Obstetrics and Gynecology, Vol.7 No.3, March 23, 2017

  ABSTRACT: Objective: To study whether there is a relation between the application of corticosteroids and occurrence of postmenopausal bleeding. Also we want to determine whether corticosteroids can cause an irregularity in a previously regular menstruation cycle. Design and Setting: Prospective cohort study in the department of anesthesiology. Patients: 209 women who received a single dosage of corticosteroids as treatment for pain. Interventions: None, observational cohort study; all women received standard care. Main outcome measures: Postmenopausal blood loss or disruption of menstruation cycle. Result: Postmenopausal blood loss or disruption of menstruation cycle were both more common 6 weeks after administration of corticosteroids, but were sometimes also reported 2 weeks after administration of corticosteroids. Conclusion: After administration of corticosteroids in a postmenopausal woman an episode of menstruation like bleeding can be expected. This is probably due to a transient drop of androstenedione. In premenopausal women a transient change in menstruation cycle can be observed.