TITLE:
Withdrawal seizure associated with high dosage of aripiprazole and fluoxetine: a case report
AUTHORS:
Jian-An Su, Shih-Yong Chou, Ching-Shu Tsai, Tai-Hsin Hung
KEYWORDS:
Aripiprazole; High Dosage; Withdrawal Seizure
JOURNAL NAME:
Open Journal of Psychiatry,
Vol.1 No.2,
July
12,
2011
ABSTRACT: Aripiprazole, a third-generation antipsychotic, has been considered to have a high safety profile and rare withdrawal symptoms. We reported the case of a schizophrenic patient with a significant obsession, who was treated with a high dosage of aripiprazole and fluoxetine. Generalized tonic-clonic seizure occurred two days after abruptly stopping these two medications. Gradually tapering aripiprazole is suggested in clinical practice, especially when using a high dosage.