TITLE:
Value of Topology Approach to Diagnose of CAD Based on Magnetocardiographic Current Distribution Maps in Difficult-to-Diagnose Patients
AUTHORS:
I. Chaikovsky, L. Stadnyuk, A. Verba, Yu. Vasetskyi, M. Budnyk, G. Mjasnikov, A. Kazmirchuk, A. Lomakovskyi
KEYWORDS:
Magnetocardiography, Coronary Artery Disease, Current Distribution, Difficult-to-Diagnose Patients, Topology Parameters
JOURNAL NAME:
World Journal of Cardiovascular Diseases,
Vol.6 No.7,
July
26,
2016
ABSTRACT: Objective: The purpose of this work is to examine the usefulness of the topological approach for analysis of current density maps during ST-T interval in detection of coronary artery disease (CAD) in patients with proved CAD but normal results of routine tests. Materials and Methods: The patient group included 123 patients. Coronary angiography was done due to chest pain. The control group consisted of 124 healthy volunteers. The MCG test was done by 4-channels MCG system installed at unshielded setting. An integral topological index Kideal, consisting of 4 parameters, has been counted. Results and Conclusions: It is shown that Kideal was higher in patient group compared to control one. Sensitivity was 87%, and specificity was 64%. The topological analysis of MCG current density maps is a valuable tool in noninvasive detection of CAD in difficult-to-diagnose patients with uninformative results of routine tests.