Article citationsMore>>
Gentilini, D., Mari, D., Castaldi, D., Remondini, D., Ogliari, G., Ostan, R., Bucci, L., Sirchia, S.M., Tabano, S., Cavagnini, F., Monti, D., Franceschi, C., Di Blasio, A.M. and Vitale, G. (2013) Role of Epigenetics in Human Aging and Longevity: Genome-Wide DNA Methylation Profile in Centenarians and Centenarians’ Offspring. Age (Dordr), 35, 1961-1973.
http://dx.doi.org/10.1007/s11357-012-9463-1
has been cited by the following article:
-
TITLE:
Anti-Aging Genes Improve Appetite Regulation and Reverse Cell Senescence and Apoptosis in Global Populations
AUTHORS:
Ian James Martins
KEYWORDS:
Anti-Aging Genes, Appetite, Environment, Nutrition, Senescence
JOURNAL NAME:
Advances in Aging Research,
Vol.5 No.1,
January
28,
2016
ABSTRACT: Appetite regulation by nutritional intervention is required early in life that involves the anti-aging gene Sirtuin 1 (Sirt 1) with Sirt 1 maintenance of other cellular anti-aging genes involved in cell circadian rhythm, senescence and apoptosis. Interests in anti-aging therapy with appetite regulation improve an individual’s survival to metabolic disease induced by gene-environment interactions by maintenance of the anti-aging genes connected to the metabolism of bacterial lipopolysaccharides, drugs and xenobiotics. Interventions to the aging process involve early calorie restriction with appetite regulation connected to appropriate genetic mechanisms that involve mitochondrial biogenesis and DNA repair in neurons. In the aging process as the anti-aging genes are suppressed as a result of transcriptional dysregulation chronic disease accelerations and connected to insulin resistance, non-alcoholic fatty liver disease (NAFLD) and neurodegenerative diseases such as Parkinson’s disease and Alzheimer’s disease. Interests in the gene-environment interaction indicate that the anti-aging gene Sirt 1that regulates food intake has been repressed early in the aging process in various global populations. The connections between Sirt 1 and other anti-aging genes such as Klotho, p66Shc (longevity protein) and Forkhead box proteins (FOXO1/ FOXO3a) have been associated with programmed cell death and alterations in these anti-aging genesregulate glucose, lipid and amyloid beta metabolism that are important to various chronic diseases.
Related Articles:
-
Bernardin Ahouty, Mathurin Koffi, David Courtin, Ilboudo Hamidou, Didier Sokouri, Innocent Abé, Laure Gineau, Thomas Konan, Lingué Kouakou, Tidou Abiba Sanogo, Enock Matovu, Bruno Bucheton, Vincent Jamonneau, Simon-Pierre N’Guetta
-
Xiting Chen
-
Mukeba Mbala Eric, Shiwei Xu, Wen Yu, Shengwei Wang, Abdul-Gafar Ahmed, Siek Darith, Mujinga Bukasa Eliane
-
Xiaoyu Liu, Duyun Peng, Youdong Wen
-
Zamina Bi Yourou Guillaume, Tiembré Issiaka, Konan Loukou Leandre, Bama Martial, Yapi Ellélé Aimé, Gouzilé Assikohon Pulchérie, Dagnan N’Cho Simplice